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This textbook is intended to serve as a reference guide to the interdisciplinary fields of nano materials, sensors and biotechnology. It demonstrates functional applications of nanotechnology in diverse areas such as environmental sensing and space habitation, to medical diagnostics and tissue regeneration. With a focus on novel materials synthesis, such as using the nano manufacturing technique of electrospinning to get the longest nano wires possible, a correlation is made of the effect of chemical, structural, and morphological features to achieve extreme materials functionality. This publication will serve as a manual to nanotechnology for both novices and experts alike, and from the materials scientist to the biophysicist and bio engineer and the medical scientist.